<\/a>karbondioksit ve su buhar\u0131.<\/p>\n\n\n\nStres ko\u015fullar\u0131 alt\u0131nda insanlar \u00f6nemli miktarda pentan, etan, izopren, karbon monoksit ve di\u011fer potansiyel toksik maddeler soluyabilir.<\/p>\n\n\n\n
Hiperventilasyon ile nefes yoluyla o kadar \u00e7ok karbondioksit kaybederiz ki doku solunumu bozulur ve k\u0131smi \"doku bo\u011fulmas\u0131na\" neden olur.<\/p>\n\n\n\n
H\u00fccreler yeterince karbondioksit salmadan oksijen al\u0131rsa, hiperventilasyon\/doku bo\u011fulmas\u0131na benzer bir durum ortaya \u00e7\u0131kar.<\/p>\n\n\n\n
Oksijen yoksunlu\u011fu yeni k\u0131rm\u0131z\u0131 kan h\u00fccrelerinin olu\u015fumu i\u00e7in uyar\u0131c\u0131lardan biridir ve bu porfirin, hem ve hemoglobin \u00fcretimini i\u00e7erir.<\/p>\n\n\n\n
Hem'in oksidasyon yoluyla ortadan kald\u0131r\u0131lmas\u0131 karbon monoksit olu\u015fturur ve bu da solunum enerji \u00fcretimini engelleyebilir.<\/p>\n\n\n\n
Ray Pete `Nefes Optimizasyonu`<\/p>\n\n\n\n
Dokular\u0131m\u0131z, h\u00fccre \u00e7\u00fcr\u00fcmesinin normal bir par\u00e7as\u0131 olarak karbon monoksit \u00fcretir. Dokulara zarar veren herhangi bir stres, art\u0131\u015f\u0131na katk\u0131da bulunur.<\/p>\n\n\n\n
Karbon monoksit ya\u015fla birlikte artar ve bu da stres hormonlar\u0131n\u0131 y\u00fckseltir.<\/p>\n\n\n\n
Karbon monoksit \u00fcreten enzim karbon monoksit taraf\u0131ndan tetiklenir.<\/p>\n\n\n\n
Karbon monoksit oksidatif enerji \u00fcretimini s\u0131n\u0131rlayabilir ve oksidatif olmayan b\u00fcy\u00fcmeyi artt\u0131r\u0131c\u0131 enerji \u00fcretim seviyelerini y\u00fckseltebilir.<\/p>\n\n\n\n
Karbon monoksit, \u00e7evresel ko\u015fullara ba\u011fl\u0131 olarak doku b\u00fcy\u00fcmesini uyarabilir veya atrofiye neden olabilir ve enflamasyonu bask\u0131layabilir veya \u015fiddetlendirebilir. Sal\u0131n\u0131m\u0131n\u0131 s\u0131n\u0131rlamak veya uzakla\u015ft\u0131r\u0131lmas\u0131n\u0131 h\u0131zland\u0131rmak terap\u00f6tik bir etkiye sahip olabilir.<\/p>\n\n\n\n
...<\/p>\n\n\n\n
Hipofiz hormonlar\u0131, ACTH, FSH, LH, TSH, prolaktin, b\u00fcy\u00fcme hormonu, POMC ve MSH (melanosit uyar\u0131c\u0131 hormon), hem oksijenaz enzimini aktive ederek h\u00fccrelerde karbon monoksit \u00fcretimini uyar\u0131r. Bu enzim, hasarl\u0131 dokularda hemoglobin ve di\u011fer proteinlerden sal\u0131nan ve serbest halde toksik olan hem molek\u00fcllerini inhibe eder (Kumar ve Bandyopadhyay, 2005). Hem bask\u0131land\u0131k\u00e7a, bu enzim serbest demir atomlar\u0131n\u0131 ve biliverdinin yan\u0131 s\u0131ra karbon monoksiti serbest b\u0131rak\u0131r. Serbest demir atomlar\u0131 oksidatif hasara neden olabilse de, biliverdin ve ondan olu\u015fan bilirubin faydal\u0131 antioksidatif etkilere sahip olabilir.<\/p>\n\n\n\n
...<\/p>\n\n\n\n
Stres, hipotalamusu etkileyerek kortikotropin salg\u0131lat\u0131c\u0131 hormon olan CRH'yi art\u0131r\u0131p hipofizin ACTH salg\u0131lamas\u0131na neden olarak ba\u015fta kortizol olmak \u00fczere adaptif hormonlar\u0131 aktive eder ve bu da adrenal bezleri harekete ge\u00e7irir. Karbon monoksit, CRH salg\u0131lanmas\u0131n\u0131 aktive eden stres kaynakl\u0131 fakt\u00f6rlerden biridir (Navarra, et ai., 2001)<\/p>\n\n\n\n
Ray Pete 'Hormonlar, enerji, ya\u015flanma ve endojen karbon monoksit'<\/p>\n\n\n\n
Biriken toksinler ve fibrozisin neden oldu\u011fu artan enerji eksikli\u011fi, solunumu ve detoksifikasyonu kontrol eden enzimleri heme etmek i\u00e7in porfirin \u00fcretimini uyarabilir ve bu da karbon monoksit ve di\u011fer solunum kar\u015f\u0131t\u0131 fakt\u00f6rlerin sal\u0131nmas\u0131na yol a\u00e7abilir.<\/p>\n\n\n\n
Ray Pete, `F\u0130BROZ: \u00d6strojen, sertlik, eksitotoksisite, ya\u015flanma - `kollajen hastal\u0131\u011f\u0131ndan` daha yayg\u0131n bir sorun<\/p>\n\n\n\n
Solunan hava iltihapl\u0131 akci\u011fer hastal\u0131klar\u0131n\u0131 te\u015fhis etmek i\u00e7in kullan\u0131l\u0131r \u00e7\u00fcnk\u00fc iltihap arac\u0131lar\u0131n\u0131n \u00e7o\u011fu u\u00e7ucu maddelerdir, ancak kanser ve artrit gibi sistemik hastal\u0131klar ve nispeten d\u00fc\u015f\u00fck stres, nefesin kimyasal bile\u015fimindeki de\u011fi\u015fikliklerle tespit edilebilir. \u00c7oklu doymam\u0131\u015f ya\u011flar ve bunlar\u0131n par\u00e7alanma \u00fcr\u00fcnleri olan aldehitler, prostaglandinler, izoprostanlar, hidrokarbonlar ve serbest radikallerin yan\u0131 s\u0131ra karbon monoksit, nitrik oksit ve karbon peroksit seviyeleri stres ko\u015fullar\u0131 alt\u0131nda y\u00fckselir.<\/p>\n\n\n\n
Ray Pete `S\u0131z\u0131nt\u0131, ya\u015flanma ve kanser`<\/p>\n\n\n\n
Mitokondri, ba\u015fta sinirler olmak \u00fczere karma\u015f\u0131k organlar\u0131n i\u015fleyi\u015fi i\u00e7in gerekli enerjinin verimli bir \u015fekilde \u00fcretilmesinden sorumludur. Mitokondride oksijenle do\u011frudan reaksiyona giren ve genellikle s\u0131n\u0131rlay\u0131c\u0131 olan enzime sitokrom c oksidaz denir.<\/p>\n\n\n\n
Bu enzim tiroid hormonuna ba\u011fl\u0131d\u0131r ve nitrik oksit, karbon monoksit, \u00f6strojen, \u00e7oklu doymam\u0131\u015f ya\u011f asitleri, serotonin, a\u015f\u0131r\u0131 serbest demir, iyonla\u015ft\u0131r\u0131c\u0131 radyasyon ve bakteriyel endotoksinler dahil bir dizi toksin taraf\u0131ndan inhibe edilir.<\/p>\n\n\n\n
\u00d6strojen mitokondriye bir\u00e7ok \u015fekilde m\u00fcdahale eder: sitokrom oksidaz fonksiyonunu bloke eder, ATP sentaz aktivitesini azalt\u0131r, hem oksijenaz\u0131 art\u0131rarak karbon monoksit ve serbest demir \u00fcretimine yol a\u00e7ar, mitokondriyal DNA'ya zarar verir ve \u00e7o\u011funlukla mitokondriyal piruvat dehidrojenaz kompleksini inhibe ederek metabolizmay\u0131 glikozdan ya\u011f oksidasyonuna y\u00f6nlendirir. Bu de\u011fi\u015fiklikler ve sitokrom oksidaz kayb\u0131, Alzheimer hastalar\u0131n\u0131n beyinlerini rahats\u0131z etmektedir. B\u00f6yle bir enerji hasar\u0131n\u0131n \u00f6strojenden kaynaklanabilece\u011fi ger\u00e7e\u011fi, bunun tek nedensel ajan oldu\u011fu anlam\u0131na gelmez. Benzer bir etkiye neden olabilecek bir\u00e7ok fakt\u00f6r vard\u0131r - radyasyon, al\u00fcminyum, endotoksinler vb.<\/p>\n\n\n\n
Ray Pete 'Demans\u0131 \u00c7\u00f6zmek: Koruyucu Progesteron'<\/p>\n\n\n\n
Solunum, y\u00fcksek organizmalar\u0131n ya\u015fam\u0131n\u0131 s\u00fcrd\u00fcrmesi i\u00e7in hayati \u00f6nem ta\u015f\u0131r ve kanserli b\u00fcy\u00fcmelerin devam etmesine ve geli\u015fmesine izin veren, h\u00fccresel ve organizma d\u00fczeyindeki solunum \"kusurlar\u0131d\u0131r\".<\/p>\n\n\n\n
Hem grubu, hemoglobin, mitokondriyal solunum enzimleri, steroid sentezleyici enzimler, tiroid hormonu olu\u015fumu, detoksifiye edici enzimler gibi \u00e7ok say\u0131da solunum i\u015flevini yerine getirdi\u011fi i\u00e7in, her h\u00fccrede nispeten ilkel bir \u015fekilde ve y\u00fcksek organizma d\u00fczeyinde biraz daha karma\u015f\u0131k bir \u015fekilde d\u00fczenlenir.<\/p>\n\n\n\n
H\u00fccre daha fazla solunum enerjisine ihtiya\u00e7 duydu\u011funda, yak\u0131t\u0131n bir k\u0131sm\u0131 porfirin \u00fcretimine y\u00f6nlendirilir, daha sonra genellikle enerji ve koruyucu fakt\u00f6rlerin verimli \u00fcretimi i\u00e7in bir \u00f6n ko\u015ful olan heme d\u00f6n\u00fc\u015ft\u00fcr\u00fcl\u00fcr. Enerji \u00fcretim sistemleri travma, oksijen eksikli\u011fi, toksinler veya bir ya da daha fazla hayati besin maddesinin eksikli\u011fi nedeniyle bloke oldu\u011funda, hem \u00fcretimi aktive olur.<\/p>\n\n\n\n
Fazla heme, heme'yi biliverdin ve karbon monoksite d\u00f6n\u00fc\u015ft\u00fcren heme oksijenaz enzimi taraf\u0131ndan yok edilir. Her iki fakt\u00f6r de h\u00fccre \u00fczerinde kanserin karakteristik bir etkisine sahiptir.<\/p>\n\n\n\n
Ray Pete, 'Karbon monoksit, \u00f6strojen ve kanserin t\u0131bbi k\u00fclt\u00fc'<\/p>\n\n\n\n
\"Karbon monoksit, oksijen varl\u0131\u011f\u0131nda bile hipoksiyi \"taklit etme\" yetene\u011fine sahiptir\" Ray Pete<\/p>\n\n\n\n
Do\u011fal olarak olu\u015fan stres alt\u0131nda, oksijen ve besin maddelerinin azalmas\u0131 \u00f6nemli bir sorundur ve bir\u00e7ok zehir, oksijen kullan\u0131m\u0131n\u0131 engelleyen siyan\u00fcr veya karbon monoksit veya \u015fekerlerin, ya\u011flar\u0131n ve amino asitlerin oksidasyonunu engelleyen etanol gibi enerji \u00fcretiminde benzer engeller olu\u015fturabilir (Shelmet, et aI., 1988).<\/p>\n\n\n\n
Oksijen h\u00fccrelerden elektronlar\u0131 uzakla\u015ft\u0131rmad\u0131\u011f\u0131nda (kimyasal olarak indirgenerek), bu elektronlar ba\u015fka bir yerde reaksiyona girerek serbest radikaller (aktif oksijen dahil) ve indirgenmi\u015f demir olu\u015fturarak uygunsuz kimyasal reaksiyonlara yol a\u00e7ar (Niknahad, et aI., 1995; MacAllister, et aI., 2011).<\/p>\n\n\n\n
Ray Pete, '\u015eeker Sorunlar\u0131'<\/p>\n\n\n\n
Doymam\u0131\u015f ya\u011f asitleri ile birle\u015fen demir, karbon monoksit olu\u015fumu ve solunum depresyonu gibi toksik etkilerle peroksiredoksiyi uyar\u0131r.<\/p>\n\n\n\n
Ray Pete, 'Ba\u011f\u0131\u015f\u0131kl\u0131k, Hormonlar ve Mantar Enfeksiyonlar\u0131'<\/p>","protected":false},"excerpt":{"rendered":"
En genel anlam\u0131yla solunum, canl\u0131 bir organizma ile \u00e7evresi aras\u0131ndaki gaz al\u0131\u015fveri\u015fi anlam\u0131na gelir. \"Doku solunumu\" terimi, kandan oksijenin h\u00fccresel emilimini ya da daha kesin bir ifadeyle, h\u00fccreler ve \u00e7evreleri aras\u0131ndaki gaz al\u0131\u015fveri\u015fini ifade eder. Bitkiler ve di\u011fer baz\u0131 organizmalar biyokimyasal olarak doku solunumuna \u00e7ok benzer bir \u015fekilde nefes al\u0131rlar. Hay\u0131r... Okumaya devam et CO2'nin \u00f6nemi\/faydas\u0131<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"iawp_total_views":105,"footnotes":""},"categories":[3],"tags":[76,45,19],"class_list":["post-152","post","type-post","status-publish","format-standard","hentry","category-3","tag-76","tag-45","tag-19","entry"],"yoast_head":"\n\u0417\u043d\u0430\u0447\u0435\u043d\u0438\u0435\/\u043f\u043e\u043b\u0437\u0438 \u043e\u0442 \u0421\u041e2 - \u0440\u0435\u0439 \u043f\u0438\u0439\u0442 \u0431\u044a\u043b\u0433\u0430\u0440\u0438\u044f<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/raypeatbg.com\/tr\/2024\/06\/11\/\u0437\u043d\u0430\u0447\u0435\u043d\u0438\u0435-\u043f\u043e\u043b\u0437\u0438-\u043e\u0442-\u0441\u043e2\/\" \/>\n<meta property=\"og:locale\" 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