{"id":162,"date":"2024-06-12T12:18:30","date_gmt":"2024-06-12T12:18:30","guid":{"rendered":"https:\/\/raypeatbg.com\/?p=162"},"modified":"2024-06-12T12:18:31","modified_gmt":"2024-06-12T12:18:31","slug":"%d0%ba%d0%b0%d0%ba%d0%b2%d0%be-%d0%b2%d1%81%d1%8a%d1%89%d0%bd%d0%be%d1%81%d1%82-%d0%b5-%d0%b5%d0%bd%d0%b4%d0%be%d1%82%d0%be%d0%ba%d1%81%d0%b8%d0%bd","status":"publish","type":"post","link":"https:\/\/raypeatbg.com\/cs\/2024\/06\/12\/%d0%ba%d0%b0%d0%ba%d0%b2%d0%be-%d0%b2%d1%81%d1%8a%d1%89%d0%bd%d0%be%d1%81%d1%82-%d0%b5-%d0%b5%d0%bd%d0%b4%d0%be%d1%82%d0%be%d0%ba%d1%81%d0%b8%d0%bd\/","title":{"rendered":"Co je to vlastn\u011b endotoxin?"},"content":{"rendered":"<p class=\"wp-block-paragraph\">B\u011b\u017en\u00e9 st\u0159evn\u00ed bakterie produkuj\u00ed molekulu obsahuj\u00edc\u00ed aminokyseliny a mastn\u00e9 kyseliny, lipopolysacharid \/LPS\/. Ta je zn\u00e1m\u00e1 jako&nbsp;<strong>\"endotoxin<\/strong>\". Endotoxin je strukturn\u00ed \u010d\u00e1st bakterie, kter\u00e1 slou\u017e\u00ed jako bari\u00e9ra proti n\u011bkter\u00fdm \"exotoxin\u016fm\" produkovan\u00fdm jin\u00fdmi mikroorganismy. Na\u0161e st\u0159eva a j\u00e1tra byla navr\u017eena tak, aby \u00fa\u010dinn\u011b ni\u010dila v\u011bt\u0161inu p\u0159\u00edtomn\u00fdch endotoxin\u016f d\u0159\u00edve, ne\u017e se dostanou do krevn\u00edho ob\u011bhu. \u017dlu\u010dov\u00e9 kyseliny maj\u00ed ve st\u0159ev\u011b detergentn\u00ed \u00fa\u010dinek, kter\u00fd chr\u00e1n\u00ed absorp\u010dn\u00ed povrchy st\u0159eva p\u0159ed \u0161kodliv\u00fdmi \u00fa\u010dinky endotoxinu.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Za norm\u00e1ln\u00edch okolnost\u00ed se j\u00e1tra sna\u017e\u00ed zabr\u00e1nit pr\u016fniku endotoxinu do krevn\u00edho ob\u011bhu a zadr\u017eov\u00e1n\u00ed estrogenu v bu\u0148k\u00e1ch. P\u0159i podv\u00fd\u017eiv\u011b, hypotyre\u00f3ze, nedostatku b\u00edlkovin a stresu j\u00e1tra umo\u017e\u0148uj\u00ed pr\u016fchod estrogenu, ani\u017e by byl zcela inaktivov\u00e1n. Inhibice endotoxin\u016f tohoto detoxika\u010dn\u00edho syst\u00e9mu je pouze jedn\u00edm ze zp\u016fsob\u016f, jak syst\u00e9mov\u011b zvy\u0161uje estrogen. Nezapome\u0148te, \u017ee estrogen je ve v\u0161ech sv\u00fdch biologick\u00fdch p\u016fsoben\u00edch excita\u010dn\u00ed a ve v\u011bt\u0161in\u011b tk\u00e1n\u00ed toto excita\u010dn\u00ed p\u016fsoben\u00ed prokazateln\u011b zp\u016fsobuje oxida\u010dn\u00ed stres.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Dr. Tom Brewer uk\u00e1zal, \u017ee nedostatek b\u00edlkovin m\u016f\u017ee v\u00e9st k nedostatku vitamin\u016f A a B, co\u017e br\u00e1n\u00ed j\u00e1tr\u016fm v inaktivaci inzul\u00ednu a estrogenu, co\u017e vede k jejich hromad\u011bn\u00ed a toxicit\u011b. Jak\u00fdkoli stres zv\u00fd\u0161\u00ed z\u00e1n\u011bt a z\u00e1n\u011bt zvy\u0161uje p\u0159\u00edjem endotoxin\u016f!<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Jak moc je to \u0161kodliv\u00e9?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">1. Cokoli, co dr\u00e1\u017ed\u00ed st\u0159eva, zvy\u0161uje vst\u0159eb\u00e1v\u00e1n\u00ed endotoxinu.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2. Pokud j\u00e1tra nedetoxikuj\u00ed estrogen sekund\u00e1rn\u011b p\u016fsob\u00edc\u00ed endotoxin, estrogen stimuluje prolaktin, ACTH, beta bu\u0148ky slinivky b\u0159i\u0161n\u00ed, NO, TNF, IL a enzymy, kter\u00e9 z PUFA vytv\u00e1\u0159ej\u00ed prostaglandiny.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">3. T\u00edm se zv\u00fd\u0161\u00ed propustnost st\u0159eva, co\u017e vede k autoimunit\u011b.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">4. Endotoxin p\u016fsob\u00ed proti \u0161t\u00edtn\u00e9 \u017el\u00e1ze, imunosupresivn\u011b a podporuje zv\u00fd\u0161enou retenci \u017eeleza v tr\u00e1vic\u00edm traktu.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">5. Bylo prok\u00e1z\u00e1no, \u017ee intenzivn\u00ed cvi\u010den\u00ed a hladov\u011bn\u00ed zvy\u0161uj\u00ed produkci kyseliny ml\u00e9\u010dn\u00e9 a amoniaku, co\u017e m\u016f\u017ee zv\u00fd\u0161it absorpci bakteri\u00e1ln\u00edho endotoxinu v tenk\u00e9m st\u0159ev\u011b. To bylo prok\u00e1z\u00e1no v pokusech s hypoglykemick\u00fdmi potkany.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">6. Karagenan zvy\u0161uje produkci a vst\u0159eb\u00e1v\u00e1n\u00ed endotoxinu.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">7. Endotoxin vede ke zv\u00fd\u0161en\u00ed hladiny estrogenu v krvi. Estrogen vytahuje albumin a vodu z krve a vytla\u010duje je do tk\u00e1n\u00ed, co\u017e vede k n\u00edzk\u00e9mu objemu krve, hyponatremii, otok\u016fm, zv\u00fd\u0161en\u00e9 sr\u00e1\u017elivosti krve ... atd.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">8. V p\u0159\u00edtomnosti nestraviteln\u00fdch potravin, jako jsou PUFA, vznik\u00e1 fermentac\u00ed lakt\u00e1t, kter\u00fd produkuje serotonin a endotoxin.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">9. Endotoxin p\u016fsob\u00ed na bu\u0148ky dr\u00e1\u017ediv\u011b, zadr\u017euje v nich Ca a estrogen, zvy\u0161uje jejich afinitu k vod\u011b a vede k mnoha poruch\u00e1m CNS a endokrinn\u00edho syst\u00e9mu.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">10. Endotoxin zvy\u0161uje peroxidaci lipid\u016f a inhibuje oxidaci gluk\u00f3zy<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Odkazy:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">http:\/\/www.jlr.org\/content\/50\/1\/1.full http:\/\/textbookofbacteriology.net\/endotoxin.html http:\/\/www.drlera.com\/bacterial_diseases\/bacterial_endotoxins.htm http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20592272 http:\/\/diabetes.diabetesjournals.org\/content\/57\/6\/1470.full http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8450032 http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8335381<\/p>","protected":false},"excerpt":{"rendered":"<p>B\u011b\u017en\u00e9 st\u0159evn\u00ed bakterie produkuj\u00ed molekulu obsahuj\u00edc\u00ed aminokyseliny a mastn\u00e9 kyseliny, lipopolysacharid \/LPS\/. Tato l\u00e1tka je zn\u00e1m\u00e1 jako \"endotoxin\". Endotoxin je strukturn\u00ed sou\u010d\u00e1st\u00ed bakterie, kter\u00e1 slou\u017e\u00ed jako bari\u00e9ra proti n\u011bkter\u00fdm \"exotoxin\u016fm\" produkovan\u00fdm jin\u00fdmi mikroorganismy. Na\u0161e st\u0159eva a j\u00e1tra byla navr\u017eena tak, aby \u00fa\u010dinn\u011b ni\u010dila v\u011bt\u0161inu p\u0159\u00edtomn\u00fdch endotoxin\u016f d\u0159\u00edve, ne\u017e se dostanou do krevn\u00edho ob\u011bhu. \u017dlu\u010d... <a class=\"more-link\" href=\"https:\/\/raypeatbg.com\/cs\/2024\/06\/12\/%d0%ba%d0%b0%d0%ba%d0%b2%d0%be-%d0%b2%d1%81%d1%8a%d1%89%d0%bd%d0%be%d1%81%d1%82-%d0%b5-%d0%b5%d0%bd%d0%b4%d0%be%d1%82%d0%be%d0%ba%d1%81%d0%b8%d0%bd\/\">Pokra\u010dovat ve\u00a0\u010dten\u00ed <span class=\"screen-reader-text\">Co je to vlastn\u011b endotoxin?<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"iawp_total_views":139,"footnotes":""},"categories":[3],"tags":[80,81],"class_list":["post-162","post","type-post","status-publish","format-standard","hentry","category-3","tag-80","tag-81","entry"],"yoast_head":"<!-- This site is optimized with the 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